Dual Enrollment Policies and Practices

The James Irvine Foundation joins educators and policymakers across the country who share a growing interest in the potential of dual enrollment. In particular, when high school students take college courses to earn transferable college credits, how are they positioned to succeed in college and career? How can we expand this opportunity to a broader range of students? Irvine's Youth program seeks to help increase the number of low-income youth in California who complete high school on time and attain a postsecondary credential by age 25. To ensure access to better educational and economic opportunities for a diverse group of students, our funding supports multiple pathways to the same destination: success in high school, college and careers. The multiple pathways approach integrates rigorous academics with demanding career and technical education, comprehensive student support services and relevant work-based learning opportunities, so that all high school students are prepared for both college and career. Research suggests that career-focused dual enrollment programs can improve secondary and postsecondary academic outcomes for a variety of students. In this context, the Concurrent Courses initiative was created to demonstrate the feasibility of using dual enrollment to enhance career and technical education pathways -- particularly for low-income youth who are struggling academically or who are within populations historically underrepresented in higher education. The Concurrent Courses initiative is being managed by the Community College Research Center (CCRC) housed at Teachers College, Columbia University. We would like to thank and recognize the authors of this brief: Joanne Wang Golann, who is a Senior Research Assistant and Katherine L. Hughes, who is the Assistant Director for Work and Education Reform Research at CCRC. The authors conducted extensive research on the dual enrollment environment in California in preparation for Concurrent Courses. This brief shares their analysis with the field to clarify the opportunities and challenges for supporting promising pathways to college

SEARS: Space Efficient And Reliable Storage System in the Cloud

Today's cloud storage services must offer storage reliability and fast data retrieval for large amount of data without sacrificing storage cost. We present SEARS, a cloud-based storage system which integrates erasure coding and data deduplication to support efficient and reliable data storage with fast user response time. With proper association of data to storage server clusters, SEARS provides flexible mixing of different configurations, suitable for real-time and archival applications. Our prototype implementation of SEARS over Amazon EC2 shows that it outperforms existing storage systems in storage efficiency and file retrieval time. For 3 MB files, SEARS delivers retrieval time of $2.5$ s compared to $7$ s with existing systems.Comment: 4 pages, IEEE LCN 201

Probing the Evolution of the Dark Energy Density with Future Supernova Surveys

The time dependence of the dark energy density can be an important clue to the nature of dark energy in the universe. We show that future supernova data from dedicated telescopes (such as SNAP), when combined with data of nearby supernovae, can be used to determine how the dark energy density $\rho_X(z)$ depends on redshift, if $\rho_X(z)$ is not too close to a constant. For quantitative comparison, we have done an extensive study of a number of dark energy models. Based on these models we have simulated data sets in order to show that we can indeed reconstruct the correct sign of the time dependence of the dark energy density, outside of a degeneracy region centered on $1+w_0 = -w_1 z_{max}/3$ (where $z_{max}$ is the maximum redshift of the survey, e.g., $z_{max}=1.7$ for SNAP). We emphasize that, given the same data, one can obtain much more information about the dark energy density directly (and its time dependence) than about its equation of state.Comment: submitted to PR

Application of One Key Question at Hinesburg Family Practice

About one half of pregnancies in the United States are unintended (mistimed or unwanted). Only 54% of pregnancies in Vermont are planned and only 29% of women in Vermont have talked to a health care worker about healthy pregnancies prior to conception. Physicians are equipped to provide the necessary information to women about preconception care and contraception, but do not regularly have these conversations with the majority of their patients. One Key Question is an initiative developed by the Oregon Foundation for Reproductive Health that allows providers to screen women patients for their pregnancy intention in the next year and appropriately respond with preconception or contraceptive counseling.https://scholarworks.uvm.edu/fmclerk/1102/thumbnail.jp

Metabolic Impacts of Using Nitrogen and Copper-Regulated Promoters to Regulate Gene Expression in Neurospora crassa.

The filamentous fungus Neurospora crassa is a long-studied eukaryotic microbial system amenable to heterologous expression of native and foreign proteins. However, relatively few highly tunable promoters have been developed for this species. In this study, we compare the tcu-1 and nit-6 promoters for controlled expression of a GFP reporter gene in N. crassa. Although the copper-regulated tcu-1 has been previously characterized, this is the first investigation exploring nitrogen-controlled nit-6 for expression of heterologous genes in N. crassa. We determined that fragments corresponding to 1.5-kb fragments upstream of the tcu-1 and nit-6 open reading frames are needed for optimal repression and expression of GFP mRNA and protein. nit-6 was repressed using concentrations of glutamine from 2 to 20 mM and induced in medium containing 0.5-20 mM nitrate as the nitrogen source. Highest levels of expression were achieved within 3 hr of induction for each promoter and GFP mRNA could not be detected within 1 hr after transfer to repressing conditions using the nit-6 promoter. We also performed metabolic profiling experiments using proton NMR to identify changes in metabolite levels under inducing and repressing conditions for each promoter. The results demonstrate that conditions used to regulate tcu-1 do not significantly change the primary metabolome and that the differences between inducing and repressing conditions for nit-6 can be accounted for by growth under nitrate or glutamine as a nitrogen source. Our findings demonstrate that nit-6 is a tunable promoter that joins tcu-1 as a choice for regulation of gene expression in N. crassa